Also known as: Delta Sleep Inducing Peptide, Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
DSIP (Delta Sleep Inducing Peptide, Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu) was first isolated from rabbit cerebral venous blood during electrically induced sleep by Monnier and Schoenenberger in 1977. Dog plasma half-life is approximately 15 minutes (Kato et al., PMID 6379493). No robust human pharmacokinetic study or randomised controlled trial exists. The proposed mechanism — NMDA and alpha-1 adrenergic pathway modulation — has not been rigorously validated. Rapid plasma clearance raises questions about whether systemically administered DSIP reaches the CNS in biologically meaningful concentrations. Community protocol: 100–750mcg SC at bedtime.
The Halflife app models your DSIP concentration curve in real time — see exactly when your dose peaks, when it troughs, and how it overlaps with other compounds in your stack. All stored on-device, no account required.