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Observational Protocol Insights

Real-world GLP-1 and peptide adherence insights from anonymised observational tracking data.

Halflife Labs publishes aggregate observational findings derived from opted-in protocol tracking data. Insights are published only after sufficient anonymised data has been collected for a specific research question and statistical confidence thresholds have been met. The dataset tracks longitudinal adherence patterns, dose escalation timing, compound stacking behavior, and protocol persistence across GLP-1, peptide, and TRT protocols.

All insights are derived from aggregate, anonymised, observational data collected from users who explicitly opted in. No individual records are identifiable. No interventional or clinical claims are made. Findings describe observed patterns, not causal relationships.
Dataset Status — May 2026
4,000+
active users
45+
compounds tracked
2,000+
opted-in participants
Wk 4
collection phase
The dataset is in active collection. Insights are published when the opted-in dataset reaches sufficient sample size and observation window for a given research question. Reports define their own cohort inclusion criteria, minimum sample thresholds, and statistical confidence requirements.
Methodology & Publication Standards

How insights are generated and when they are published.

Observational Design

All insights are observational, non-interventional, and retrospective. Halflife does not assign protocols, control dosing, or influence user behavior. Findings describe observed aggregate patterns in self-reported tracking data — not causal relationships.

Publication Thresholds

Reports are published only when the opted-in dataset reaches a predefined sample size and observation window for a specific research question. Each report defines its own cohort inclusion criteria, minimum sample size, and statistical confidence threshold.

Read the full methodology →
Upcoming Reports

Research questions the current dataset is designed to answer.

Each report will be published when its target sample size and observation window are met. Target thresholds are listed per report.

📊
GLP-1 ADHERENCE
CURRENTLY ONGOING
Tirzepatide vs. semaglutide: real-world adherence comparison at week 12

Comparative week-by-week adherence rates, dose escalation timing, side effect frequency, and dropout patterns between tirzepatide and semaglutide users in a self-managed population. Observational comparison — not head-to-head trial.

Target: 500 opted-in users Window: 12 weeks Entities: Tirzepatide · Semaglutide
💉
STACKING PREVALENCE
CURRENTLY ONGOING
Compound stacking prevalence among GLP-1 users

Which compounds are most commonly added to tirzepatide and semaglutide protocols, in what order they are introduced, and observed adherence changes after stacking. Compounds of interest: BPC-157, TB-500, CJC-1295/Ipamorelin, testosterone.

Target: 750 opted-in users Window: 16 weeks Entities: Tirzepatide · Semaglutide · BPC-157 · CJC-1295
📈
DOSE ESCALATION
CURRENTLY ONGOING
Dose escalation timing in compounded tirzepatide protocols

Observed starting doses, escalation intervals, and time to steady state in compounded tirzepatide users compared to FDA label recommendations. Includes adherence correlation by escalation speed. Observational only — no dosing recommendations.

Target: 1,000 opted-in users Window: 20 weeks Entities: Tirzepatide
🧬
PROTOCOL COMPLEXITY
NOT STARTED
TRT + peptide protocols: adherence by protocol complexity

How observed adherence rates change as users add compounds to a base TRT protocol — from single-compound TRT to 4+ compound stacks including GH secretagogues, peptides, and GLP-1 medications. Identifies observed adherence inflection points by stack size.

Target: 2,000 opted-in users Window: 24 weeks Entities: Testosterone Cypionate · CJC-1295 · Ipamorelin · BPC-157
Research Themes

Topics the Halflife dataset is structured to investigate.

GLP-1 Adherence Patterns

Week-by-week adherence, dropout timing, and protocol persistence for tirzepatide and semaglutide users.

Compound Stacking Behavior

Which compounds are combined, in what sequence, and how stacking affects observed adherence and protocol persistence.

Dose Escalation Timing

Real-world escalation intervals compared to label recommendations for GLP-1 medications.

Protocol Complexity and Persistence

How the number of simultaneously tracked compounds correlates with observed adherence rates over time.

TRT + Peptide Longitudinal Tracking

Long-term adherence patterns for testosterone cypionate protocols with and without concurrent peptide stacking.

Side Effect and Symptom Patterns

Reported side effect frequency correlated with compound type, dose level, and protocol duration.

Data Collection Layer

The Halflife app is the source of all protocol tracking data used in this research.

Every insight published on this page is derived from anonymised injection logs, dose records, weight entries, and symptom reports collected through the Halflife iOS app. Users who opt in to research contribution have their protocol data aggregated at the cohort level for analysis. Published findings are surfaced directly in the app's Discover tab as they become available.

Learn about the app → Download on App Store
Research Collaboration & Enterprise Access

Access observational protocol data for institutional research or integration.

Halflife Labs provides structured access to anonymised, aggregated protocol outcome data for academic researchers, telehealth platforms, and pharmaceutical companies. All access models support IRB-compatible research frameworks and follow opt-in consent standards.

Learn about partnership models →

Research collaboration inquiries: contact@halflife-labs.com

CASE STUDIES
Protocol outcome reports
Cohort-based adherence and outcome data for specific compound combinations.
COMPOUND DATABASE
45 compound profiles
Citation-backed half-life values, mechanism summaries, and dosing references.
PROTOCOL TRACKER
Download the app
Injection logging, concentration curves, and syringe calculator for 45 compounds.