Also known as: ERRα/β/γ pan-agonist, exercise mimetic compound
SLU-PP-332 is a small-molecule pan-agonist at estrogen-related receptors ERRα (EC₅₀ 98nM), ERRβ (EC₅₀ 230nM), and ERRγ (EC₅₀ 430nM). Mouse in vivo pharmacokinetics at 30mg/kg i.p. show an estimated half-life of ~3.5 hours (Billon et al., PMC11584170). No human pharmacokinetic data exists. The compound activates the PGC-1α coactivator pathway in skeletal muscle, inducing mitochondrial biogenesis and fatty acid oxidation gene programs — mimicking molecular responses to aerobic exercise. Preclinical tool compound only; no IND filed with the FDA.
The Halflife app models your SLU-PP-332 concentration curve in real time — see exactly when your dose peaks, when it troughs, and how it overlaps with other compounds in your stack. All stored on-device, no account required.